RegPep2018 is the 22nd Symposium of the International Regulatory Peptide Society (IRPS), an international federation of scientists committed to progress in basic research on the biology and physiology of peptides, and translation of that basic research into clinical gains and public health benefit.
RegPep2018 will be a critical meeting in the peptide field, as in previous years, by explicitly uniting basic research and clinical research in regulatory peptides. However, the emphasis on the emergence of peptides as therapeutic agents, for the 2018 conference, will create a synergism between the basic and clinical aspects of the peptide field that will potentially have a strong impact on progress in this area to the benefit of the public health in the coming years. This translational focus will be specially emphasized at RegPep2018, which will be held for the first time ever in Latin America, on Acapulco Diamante, Mexico, in September 22-25, 2018.
RegPep past meetings have been held in: Asilomar (USA, 1976), Beito (Norway, 1978), Cambridge (UK, 1980), Stockholm (Sweden, 1982), Rochester (USA, 1984), Vancouver (Canada, 1986), Shizuoka (Japan, 1988), Timmerndorfer Strand (Germany, 1990), Luewen (Belguim 1992), Santa Barbara (USA, 1994), Copenhagen (Denmark, 1996), Mackinac Island (USA, 1998), Cairns (Australia, 2000), Boston (USA, 2002), Toulouse (France, 2004), Hakone (Japan, 2006), Santa Bárbara (USA, 2009), Belfast (Ireland, 2010), Copenhagen (Denmark, 2012), Kyoto (Japan, 2014), Rouen (France, 2016).
The history of RegPep and the International Regulatory Peptide Society can be found on its website (regulatorypeptide.org). The IRPS exists to make possible every other year the international regulatory peptide meeting called RegPep, of which RegPep2018 is the 22nd. A brief history: the first regulatory peptide discovered was secretin (by Starling and Bayliss, in 1902); the ‘prime regulatory peptide’ and the one of greatest current medical consequence, insulin, was discovered by Banting and Best in the early 1920’s. The sequence of the nine-amino acid-long hormone oxytocin, and the first laboratory synthesis, was accomplished in 1954 by du Vigneaud. Victor Mutt and others began the systematic identification of peptides of the gut in the 1960s, and established a method for detecting and chemically identifying peptides of the gut by their C-terminal amidation (about half of all regulatory peptides are amidated), that resulted in the discovery of many more biologically active peptides.
In the years since, many other peptides like CCK, VIP, and enkephalin have been discovered which, like insulin, control metabolism through regulation of cellular uptake of fuels including sugar, protein, and lipids, behavior, the proliferation of cells, the immune system, etc. Peptides represent a diverse symphony of regulators of most bodily and mental functions, and as such are a rich source for understanding human physiology and developing human therapeutics. The IRPS, and RegPep, exist to serve that purpose. The IRPS was established and held its first international conference in 1976 because physiologists and pharmacologists who knew of Mutt’s work realized that it would result in an explosion in new knowledge about regulation of human physiology by peptides, and many new therapeutic opportunities to treat human diseases of the gut and peripheral tissues. Another great breakthrough in the field came when the brain factors that control pituitary hormone secretion were discovered to be peptides, and sequenced and chemically synthesized by Schally and Guillemin and their colleagues. As more peptide sequencing by colleagues of Guillemin and Schally, and of Mutt, occurred, it was realized that many of the ‘gut’ and ‘hypophysiotropic’ peptides were also expressed in the brain, and the science of neuroendocrinology became an integral part of what is today called ‘neuroscience’.
Throughout these years, RegPep has been a constant source of intellectual renewal in the promise of peptides for understanding fundamental neuroscience and endocrinology, and focusing this knowledge clinically and, particularly in this coming year, in new drug discovery. RegPep celebrates the triad of physiology, medicine, and pharmacology in both a practical and an intellectual way. Intellectually, knowledge about new peptides in various species is of basic interest no matter in what species the initial discoveries are made. Information about the pharmacological effects of administered peptides in humans, or detection of altered peptide levels in various human diseases such as hypoparathyroidism, diabetes, epilepsy, and so forth allows confirmation of the importance of the new peptide in clinical medicine. Finally, as a practical matter, peptide actions in contributing to diseases suggest drugs that act by blocking their receptors, while peptide actions in ameliorating disease suggest drugs that act by stimulating their receptors.
Lee E. Eiden (NIH, USA, Chair of RegPep2018), Limei Zhang (UNAM, Mexico, Co-Chair of RegPep2018)
RegPep2018 is being convened to unite basic, translational and pharmaceutical scientists who study, and develop therapeutically, biological peptides with key physiological functions in the brain, the gut, and the cardiovascular and immune systems to affect processes of cognition and mood, digestion and metabolism, blood pressure and inflammation and surveillance of cell malignancy.
Peptides are key regulators in health and disease, including depression, anxiety, PTSD, neurodegeneration, obesity, diabetes, hypertension, allergy, autoimmune disease, reproductive disorders and cancer. Within the last five years, more peptide-based drugs have been approved by the US Food and Drug Administration for the treatment of human disease than in the previous 50 years. Helping to create a ‘revolution of opportunity’ for leveraging knowledge about peptide physiology that allows identification of novel drug targets, and the creation of innovative new drugs, is the aim of our meeting.
Accordingly, RegPep2018 will feature presentations by science leaders in the fields of peptide biology in five thematic areas (central nervous system, cardiovascular, metabolism, cancer, anti-microbials), and commentary and perspectives by academic, pharma and government leaders that collectively help guide drugs safely to final use in the clinic and in everyday medical practice.
|Eiden, Lee E. (Chair, USA) ,||Zhang, Limei (Co-Chair, México)|
|Aguilera, Greti (USA)||Lujan, Rafael (Spain)|
|Antunes-Rodriguez, José (Brazil)||Mahata, Sushil (USA)|
|Banks, William (USA)||Miyata, Atsuro (Japan)|
|Baram, Tallie Z. (USA)||Moody, Terry (USA)|
|Brown, Colin (New Zealand)||Pemberton, Chris (New Zealand)|
|Chow, Billy K.C. (China)||Pintér, Erika (Hungary)|
|Depoortere, Inge (Belgium)||Pisegna, Joseph (USA)|
|Gainer, Harold (USA)||Reglödi, Dora (Hungary)|
|Gozes, Illana (Israel)||Russell, John A. (UK)|
|Herzig, Karl-Heinz||Seong, Jae Young (Korea)|
|Hiriart, Marcia (Mexico)||Shioda, Seiji (Japan)|
|Hökfelt, Tomas (Sweden)||Taché, Yvette (USA)|
|Joseph-Bravo, Patricia (Mexico)||Vaudry, Hubert (France)|
|Kershenobich, David (Mexico)||Vivas, Laura (Argentina)|
|Kofler, Barbara (Austria)||Waschek, James (USA)|
Flyer of RegPep2018
Download PDF (published November 11th, 2017)
First announcement: Call for symposium/speaker proposals
Download PDF (published December 15th, 2017)
Second announcement: Submit your abstract now
Download PDF (published February 28th, 2018)
Third announcement: Join us at RegPep2018!
Download PDF (Published april 11th, 2018)
Click schedule to enlarge
Download the complete scientific program (last update 9th april, 2018)
Registration fee for all conference participants include:
|Early Bird (before May 4, 2018, 5pm GMT-5:00)***||Regular (May 4, 2018, 5:01 pm GMT-5 to 31st August 2018, 5pm GMT-5:00)||On site (After 31st August 2018, 5pm GMT-5:00)|
|Industry / Government delegate||500 USD||600 USD||660 USD|
|Investigator *||400 USD||500 USD||560 USD|
|Postdoctoral fellow *,**||300 USD||400 USD||460 USD|
|Student *,**||200 USD||300 USD||360 USD|
|Guest ****||100 USD||100 USD||100 USD|
* Participants from Latin-American and other developing countries holding or participating in a government or institution funded research project in the last 3 years can apply for a reduced fee (40%). Please send an email to firstname.lastname@example.org with supporting documentation and we will send you a new link for registration with the reduced fee.
** Please send an email to validate your trainee status.
*** Travel award applicants should register and submit your application before this deadline.
**** Guests are welcome to join the welcome reception and the lunch but are not expected to attend the scientific sessions. The cost of $50 USD also applies to guests for the conference dinner / party.
Submit your abstract via email (email@example.com), together with a copy of the PayPal receipt of your registration.
Please format the abstract as follows:
15th of March 2018: abstracts submitted by this date will be evaluated collegially by Program Committee of the IAC for contributed talks selection and for travel awards (these cover the awardee's local transportation and accommodations including hotel and meals).
30th June 2018: abstract submission closes.
The Princess Mundo Imperial a 5-star resort and conference center, has offered us attractive prices, and also to respect those prices for 3 days prior and 3 days after the RegPep2018.
If you want to book with this discount price, please send us your registration and we will send you the code for the discount hotel booking.
In case you would prefer to use a travel agency, please let us know your booking. The reason for this petition is that we have made a commitment for a minimum number of room occupancy for the usage of meeting facilities.
Blessed by warm waters and sunshine 365 days a year, gorgeous beaches, scenery of unrivaled beauty, and hospitable, friendly people, Acapulco offers a casual, relaxed atmosphere. It has one of the most stunning bay views offered by any coastal resort. The newer Acapulco Diamante area situated from Puerto Marques Bay to Revolcadero Beach offers first-class resorts, residential developments, modern shopping malls, 4 spectacular 18-holes golf courses, and a one of kind tourist complex offering relaxation, business, entertainment and wellbeing, all in a single destination with a luxurious hotel, an spa, an avant-garde performance and entertainment venue, and a modern Convention and Exposition Center.
Find out more by downloading the official guide here: Download PDF
The Hotel offers some amenities within the resort and some companies that work in partnership with the hotel have offered their services, please if you are interested, contact them directly or in situ at their stands in the hotel :
XTASEA: Offering "The world's longest over-sea zip line". www.xtasea.mx
Potro Viajes: Offers "Guided tours through the city, sport fishing, diving spectacle, diving , and Historic Tours". Please ask for information with the concierge.
Local Airlines travelling to Acapulco are listed below:
In Mexico City we have 5 main bus stations:
Terminal Sur (South station)
Terminal Norte (North station)
Terminal Observatorio (East station)
Terminal TAPO (West station)
Terminal Aeropuerto (Airport Station)
In the Terminal del Sur, Taxqueña, there are quite a few departures to Acapulco Diamante. From the Terminal del Norte, the TAPO and Aeropuerto (International Airport of Mexico City), there are also departures to Acapulco Diamante (terminal del Norte) and Acapulco. The bus takes an average of 5 hours from Mexico City to Acapulco. A Deluxe ticket costs around 40 USD and the standard ticket around 30 USD.
Please be aware that the Hotel Princess is located in Acapulco Diamante, 2.4 Km from Acapulco Diamante bus terminal, and 16.8 Km from the Acapulco Centro bus terminal.
Your Mexican colleagues look forward to welcome you in RegPep2018! Left to right: Jean-Louis Charli, Vito Hernández, (Lee E.Eiden, NIH, USA), Limei Zhang, Raúl Aguilar-Roblero and Patrícia Joseph-Bravo, January 11, 2018
Webmasters: Vito Hernández & Hernán Barrio
Last update: February 28th, 2018