RegPep2018 is the 22nd Symposium of the International Regulatory Peptide Society (IRPS), an international federation of scientists committed to progress in basic research on the biology and physiology of peptides, and translation of that basic research into clinical gains and public health benefit.
RegPep2018 will be a critical meeting in the peptide field, as in previous years, by explicitly uniting basic research and clinical research in regulatory peptides. However, the emphasis on the emergence of peptides as therapeutic agents, for the 2018 conference, will create a synergism between the basic and clinical aspects of the peptide field that will potentially have a strong impact on progress in this area to the benefit of the public health in the coming years. This translational focus will be specially emphasized at RegPep2018, which will be held for the first time ever in Latin America, on Acapulco Diamante, Mexico, in September 22-25, 2018.
RegPep past meetings have been held in: Asilomar (USA, 1976), Beito (Norway, 1978), Cambridge (UK, 1980), Stockholm (Sweden, 1982), Rochester (USA, 1984), Vancouver (Canada, 1986), Shizuoka (Japan, 1988), Timmerndorfer Strand (Germany, 1990), Luewen (Belguim 1992), Santa Barbara (USA, 1994), Copenhagen (Denmark, 1996), Mackinac Island (USA, 1998), Cairns (Australia, 2000), Boston (USA, 2002), Toulouse (France, 2004), Hakone (Japan, 2006), Santa Bárbara (USA, 2009), Belfast (Ireland, 2010), Copenhagen (Denmark, 2012), Kyoto (Japan, 2014), Rouen (France, 2016).
The history of RegPep and the International Regulatory Peptide Society can be found on its website (regulatorypeptide.org). The IRPS exists to make possible every other year the international regulatory peptide meeting called RegPep, of which RegPep2018 is the 22nd. A brief history: the first regulatory peptide discovered was secretin (by Starling and Bayliss, in 1902); the ‘prime regulatory peptide’ and the one of greatest current medical consequence, insulin, was discovered by Banting and Best in the early 1920’s. The sequence of the nine-amino acid-long hormone oxytocin, and the first laboratory synthesis, was accomplished in 1954 by du Vigneaud. Victor Mutt and others began the systematic identification of peptides of the gut in the 1960s, and established a method for detecting and chemically identifying peptides of the gut by their C-terminal amidation (about half of all regulatory peptides are amidated), that resulted in the discovery of many more biologically active peptides.
In the years since, many other peptides like CCK, VIP, and enkephalin have been discovered which, like insulin, control metabolism through regulation of cellular uptake of fuels including sugar, protein, and lipids, behavior, the proliferation of cells, the immune system, etc. Peptides represent a diverse symphony of regulators of most bodily and mental functions, and as such are a rich source for understanding human physiology and developing human therapeutics. The IRPS, and RegPep, exist to serve that purpose. The IRPS was established and held its first international conference in 1976 because physiologists and pharmacologists who knew of Mutt’s work realized that it would result in an explosion in new knowledge about regulation of human physiology by peptides, and many new therapeutic opportunities to treat human diseases of the gut and peripheral tissues. Another great breakthrough in the field came when the brain factors that control pituitary hormone secretion were discovered to be peptides, and sequenced and chemically synthesized by Schally and Guillemin and their colleagues. As more peptide sequencing by colleagues of Guillemin and Schally, and of Mutt, occurred, it was realized that many of the ‘gut’ and ‘hypophysiotropic’ peptides were also expressed in the brain, and the science of neuroendocrinology became an integral part of what is today called ‘neuroscience’.
Throughout these years, RegPep has been a constant source of intellectual renewal in the promise of peptides for understanding fundamental neuroscience and endocrinology, and focusing this knowledge clinically and, particularly in this coming year, in new drug discovery. RegPep celebrates the triad of physiology, medicine, and pharmacology in both a practical and an intellectual way. Intellectually, knowledge about new peptides in various species is of basic interest no matter in what species the initial discoveries are made. Information about the pharmacological effects of administered peptides in humans, or detection of altered peptide levels in various human diseases such as hypoparathyroidism, diabetes, epilepsy, and so forth allows confirmation of the importance of the new peptide in clinical medicine. Finally, as a practical matter, peptide actions in contributing to diseases suggest drugs that act by blocking their receptors, while peptide actions in ameliorating disease suggest drugs that act by stimulating their receptors.
Lee E. Eiden (NIH, USA, Chair of RegPep2018), Limei Zhang (UNAM, Mexico, Co-Chair of RegPep2018)
RegPep2018 is being convened to unite basic, translational and pharmaceutical scientists who study, and develop therapeutically, biological peptides with key physiological functions in the brain, the gut, and the cardiovascular and immune systems to affect processes of cognition and mood, digestion and metabolism, blood pressure and inflammation and surveillance of cell malignancy.
Peptides are key regulators in health and disease, including depression, anxiety, PTSD, neurodegeneration, obesity, diabetes, hypertension, allergy, autoimmune disease, reproductive disorders and cancer. Within the last five years, more peptide-based drugs have been approved by the US Food and Drug Administration for the treatment of human disease than in the previous 50 years. Helping to create a ‘revolution of opportunity’ for leveraging knowledge about peptide physiology that allows identification of novel drug targets, and the creation of innovative new drugs, is the aim of our meeting.
Accordingly, RegPep2018 will feature presentations by science leaders in the fields of peptide biology in five thematic areas (central nervous system, cardiovascular, metabolism, cancer, anti-microbials), and commentary and perspectives by academic, pharma and government leaders that collectively help guide drugs safely to final use in the clinic and in everyday medical practice.
|Eiden, Lee E. (Chair, USA)||Zhang, Limei (Co-Chair, México)|
|Aguilera, Greti (USA)||Lujan, Rafael (Spain)|
|Antunes-Rodriguez, José (Brazil)||Mahata, Sushil (USA)|
|Banks, William (USA)||Miyata, Atsuro (Japan)|
|Baram, Tallie Z. (USA)||Moody, Terry (USA)|
|Brown, Colin (New Zealand)||Pemberton, Chris (New Zealand)|
|Chow, Billy K.C. (China)||Pintér, Erika (Hungary)|
|Depoortere, Inge (Belgium)||Pisegna, Joseph (USA)|
|Gainer, Harold (USA)||Reglödi, Dora (Hungary)|
|Gozes, Illana (Israel)||Russell, John A. (UK)|
|Hiriart, Marcia (Mexico)||Seong, Jae Young (Korea)|
|Hökfelt, Tomas (Sweden)||Shioda, Seiji (Japan)|
|Joseph-Bravo, Patricia (Mexico)||Taché, Yvette (USA)|
|Kershenobich, David (Mexico)||Vaudry, Hubert (France)|
|Kofler, Barbara (Austria)||Vivas, Laura (Argentina)|
|Leng, Gareth (UK)||Waschek, James (USA)|
It is our great pleasure to announce the 22nd International Symposium on Regulatory Peptides, RegPep2018, under the auspice of the International Regulatory Peptide Society (IRPS) and the National Autonomous University of Mexico (UNAM), which will be held on September 22-25, 2018, at the Resort and Conference Center Princess Mundo Imperial, in the newly developed Riviera Diamante, Acapulco, Mexico.
RegPep2018 is a unique venue in which basic and clinician scientists studying the physiology and pathophysiology of peptide actions, integrated from a brain-body-behavior perspective in health and disease, can learn how their key research questions relate to therapeutics.
RegPep2018 will feature cutting-edge findings across all aspects of peptide function, in translationally relevant areas of research.
Together with the Local Organizing Committee (LOC) and the International Advisory Committee (IAC) of RegPep2018, we would like to invite you to submit symposium/speaker proposals, which will be peer-reviewed and classified as contributed talks in symposia for RegPep2018.
Participants including both speakers, and poster presenters chosen by the RegPep2018 Program Committee, will have the possibility to contribute as authors to one of two Special Issues arising from the conference to be published in Frontiers in Endocrinology/Neuroscience and in The Annals of the New York Academy of Sciences.
Proposals for symposia should be submitted to email@example.com, cc to firstname.lastname@example.org and email@example.com. Symposium proposals should include name, e-mail address and laboratory website URL of each speaker, title of each presentation, and a brief paragraph on the importance of the symposium topic to the mission and scope of RegPep2018 (regpep2018.facmed.unam.mx). We strongly recommend you to not propose more than 3 potential speakers, leaving space for contributed talks from general submissions, selected by the program sub-committee of the IAC.
You are warmly welcome to self-propose to be a speaker. In this case, please provide us your title and an abstract with at least one publication in the field of your own and other recent and/or relevant literature. Please have a look of the already existed topics for proposed symposia (apendix).
Deadline for symposium/speaker proposal/self-proposal:
31st of January 2018
Participants in selected symposia will be offered complimentary hotel accommodations and attendance at Conference Dinner, but will be expected to register in advance for RegPep2018.
Website registration opens on 15th January 2018:
Decision about acceptance of the symposium proposals will be made and communicated to proposers before February 15th, 2018.
We look forward to seeing you at RegPep2018.
Suggested symposium and workshop topics so far:
Additional topic suggestions are welcome. The Program Committee will announce preliminary program in January 2018.
Click flyer to enlarge
Preliminary scientific program (last update 15th January 2018)
Click program to enlarge
Refining Opioid Receptor Signaling to Improve the Therapeutic Index
Peptide-degrading enzymes and the control of peptide action in vivo
The heart of the brain: the hypothalamus and its hormones
Oxytocinergic gating of social reward
Hypothalamic hormones; from neuroendocrinology to therapy of cancer and other diseases and conditions
Peptide Pioneers: A Roundtable featuring historical and future perspectives by leaders in the field
Registration fee for all conference participants include:
|Early Bird (before 15th March 2018)***||Regular (16th March to 31st August 2018)||On site (from 1st September 2018)|
|Industry / Government delegate||500 USD||600 USD||660 USD|
|Investigator *||400 USD||500 USD||560 USD|
|Postdoctoral fellow *,**||300 USD||400 USD||460 USD|
|Student *,**||200 USD||300 USD||360 USD|
|Guest ****||100 USD||100 USD||100 USD|
* Participants from Latin-American and other developing countries holding or participating in a government or institution funded research project in the last 3 years can apply for a reduced fee (40%). Please send an email to firstname.lastname@example.org with supporting documentation and we will send you a new link for registration with the reduced fee.
** Please send an email to validate your trainee status.
*** Travel award applicants should register and submit your application before this deadline.
**** Guests are welcome to join the welcome reception and the lunch but are not expected to attend the scientific sessions. The cost of $50 USD also applies to guests for the conference dinner / party.
Please screen-print the receipt of your payment from PayPal and email to email@example.com with subject field "regpep2018 registration fee: yourfirstname_yourfamilyname_yourinstitution". This insures proper notation of your registration in the records of UNAM, our sponsoring institution
Hotel booking through the RegPep2018 Secretariat will be opened on 15th January 2018.*
* Please note that the Princess Mundo Imperial, a 5-star resort and conference center, has offered us attractive prices, and also to respect those prices for 3 days prior and 3 days after the RegPep2018. The payment will be made through the Faculty of Medicine, UNAM - there will not be any 3rd party managing this issue. We would like to ask you for your kind cooperation by booking through the RegPep2018 Secretariat that would facilitate us, your academic peers, to organize efficiently the RegPep2018. If you would prefer to use a travel agency, please let us know your booking. The reason for this petition is that we have made a commitment for a minimum number of room occupancy for the usage of meeting facilities.
Submit your abstract via email (firstname.lastname@example.org), together with a copy of the PayPal receipt of your registration.
Please format the abstract as follows:
15th of March 2018: abstracts submitted by this date will be evaluated collegially by Program Committee of the IAC for contributed talks selection and for travel awards (these cover the awardee's local transportation and accommodations including hotel and meals).
30th June 2018: abstract submission closes.
|Charles Allen||USA||Oregon Health Sciences University|
|Faisal Amin||Denmark||University of Copenhagen|
|Raúl Aguilar-Roblero||México||UNAM, Mexico City|
|Greti Aguilera||USA||NIH, Bethesda|
|William A. Banks||USA||University of Washington, Seattle|
|Tallie Z. Baram||USA||University of California-Irvine|
|Laura Bohn||USA||Scripps Institute, Jupiter|
|Ruud M. Buijs||México||UNAM, Mexico City|
|Jean-Louis Charli||México||UNAM, Cuernavaca|
|Bice Chini||Italy||CNR Institute of Neuroscience, Milan|
|Christopher Colwell||USA||University of California-Los Angeles|
|Inge Depoortere||Belgium||TARGID, Leuven|
|Jan Deussing||Germany||Max-Planck Institute, Munich|
|Francesco Ferraguti||Austria||Med. Univ. Innsbruck|
|Vincent Geenen||Belgium||University Hospital of Liege|
|Ki Ann Goosens||USA||MIT, Massachusetts|
|Gilles Guillon||France||IGF, Montpellier|
|Illana Gozes||Israel||Tel Aviv University|
|Patricia Grasso||USA||Albany Medical Colege|
|Valery Grinevich||Germany||Max-Planck Institute, Heidelberg|
|Jom Hammack||USA||University of Vermont|
|James P. Herman||USA||University of Cincinnati|
|Vito Hernández||México||UNAM, Mexico City|
|Patricia Joseph||México||UNAM Cuernavaca|
|Barbara Kofler||Austria||Paracelsus Medical Univ, Salzburg|
|Eric G. Krause||USA||University of Florida, USA|
|Gareth Leng||UK||University of Edinburgh|
|Mike Ludwig||UK||University of Edinburgh|
|Sushil Mahata||USA||University of California-San Diego|
|Robert C. Malenka||USA||Stanford University|
|Maurice Manning||USA||University of Toledo, Ohio|
|Terry Moody||USA||NCI, NIH, Bethesda|
|David Murphy||UK||University of Bristol|
|Gwen Murphy||USA||NCI, NIH, Bethesda|
|Inga D. Neumann||Germany||University of Regensburg|
|Diego Perez-Tilve||USA||University of Cincinnati, Ohio|
|Hugh Piggins||UK||University of Manchester|
|Erika Pintér||Hungary||University of Pecs|
|Joseph Pisegna||USA||University of California-Los Angeles|
|William Z. Potter||USA||NIMH, NIH, Bethesda|
|Dora Reglödi||Hungary||University of Pecs|
|Andrew Russo||USA||University of Iowa|
|Stephen Salton||USA||Mount Sinai University|
|Matthew Thakur||USA||Thomas Jefferson University,Pensilvania|
|Andrew V. Schally||USA||University of Miami|
|Seiji Shioda||Japan||Showa University, Tokyo|
|Rae Silver||USA||Columbia University, New York|
|Valerie Simonneaux||France||INCI, Strasbourg|
|Jill Smith||USA||Georgetown University, Washington, D.C.|
|Andreas Stengel||Germany||University of Tübingen|
|Ichiro Takasaki||Japan||University of Toyama|
|Yvette Taché||USA||University of California-Los Angeles|
|David Vaudry||France||University of Rouen|
|Alexa Veneema||USA||Michigan State University|
|James A. Waschek||USA||University of California-Los Angeles|
|Nils Wierup||Sweden||Lund University|
|W. Scott Young||USA||NIMH, Bethesda|
|Rhongjie Yu||China||Jinan University Guangzhou, Guangdong|
|Xiao-Dong Wang||China||Zhejiang University|
|Huahyuan Zhang||China||Guangdong Medical University|
|Limei Zhang||México||UNAM, Mexico City|
Your Mexican colleagues look forward to welcome you in RegPep2018! Left to right: Jean-Louis Charli, Vito Hernández, (Lee E.Eiden, NIH, USA), Limei Zhang, Raúl Aguilar-Roblero and Patrícia Joseph-Bravo, January 11, 2018
Webmasters: Vito Hernández & Hernán Barrio
Last update: January 19th, 2018